Time to glucose peak during an oral glucose tolerance test identifies prediabetes risk

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Longer time to peak glucose during the oral glucose tolerance test increases cardiovascular risk score and diabetes prevalence

INTRODUCTION The pattern of glucose levels during an oral glucose tolerance test (OGTT) may be useful for predicting diabetes or cardiovascular disease (CVD). Our aim was to determine whether the time to peak glucose during the OGTT is associated with CVD risk scores and diabetes. METHODS Individuals with impaired fasting glucose (IFG) were enrolled in this observational study. Participants w...

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Prediction of Glucose Tolerance without an Oral Glucose Tolerance Test

Introduction Impaired glucose tolerance (IGT) is diagnosed by a standardized oral glucose tolerance test (OGTT). However, the OGTT is laborious, and when not performed, glucose tolerance cannot be determined from fasting samples retrospectively. We tested if glucose tolerance status is reasonably predictable from a combination of demographic, anthropometric, and laboratory data assessed at one ...

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Assessing the shape of the glucose curve during an oral glucose tolerance test.

OBJECTIVE The oral glucose tolerance test (OGTT) is used to define the status of glucose tolerance based on the plasma glucose level at 120 min. The purpose of the present study was to identify parameters that determine the shape of the plasma glucose course measured at 0, 30, 60, 90, and 120 min during an OGTT. RESEARCH DESIGN AND METHODS OGTT data from 551 subjects (485 with normal glucose ...

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Glucose Absorption in Gestational Diabetes Mellitus During an Oral Glucose Tolerance Test

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Assessing 1-h plasma glucose and shape of the glucose curve during oral glucose tolerance test.

OBJECTIVE To assess the cutoff values at different time points for impaired glucose regulation (IGR) and diabetes, the glucose curve and isolated 1-h hyperglycemia were monitored during an oral glucose tolerance test (OGTT). METHODS Two thousand eight hundred and eighty-six subjects (1300 men and 1586 women) were recruited to have an OGTT. Plasma was collected at 0, 30, 60, 120, and 180 min t...

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ژورنال

عنوان ژورنال: Clinical Endocrinology

سال: 2017

ISSN: 0300-0664

DOI: 10.1111/cen.13416